Thymosin Alpha-1

Searching to buy Thymosin Alpha-1 5mg for your research? Thymosin Alpha-1 is a synthetic 28-amino acid peptide derived from thymosin fraction 5 of the bovine thymus gland. One of the most well-researched immune-modulating peptides in laboratory and preclinical studies. Its role in T-cell differentiation and activation cytokine regulation is known to support immune system function as a whole.

Important Research Disclaimer:

Thymosin Alpha-1 5mg is an investigational novel drug used only for research purposes.It is not approved by the F.D.A.for human consumption, immune therapy, vaccine enhancement or any other medical use. This product is for researchers use only and not intended for diagnostic or therapeutic purposes. Not for individual or private use.

What Is Thymosin Alpha-1?

Thymosin Alpha-1 is a 28-amino acid peptide that is highly conserved and has the following sequence:Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OHMolecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅Molecular Weight: 3,108.3 DaThymosin-alpha 1, which was first isolated from thymosin fraction 5 in the late 1970s by the American researcher Dr. Allan Goldstein, has evolved into a leading peptide in immunology research. Thymosin Alpha-1 mainly targets T-cells to induce their differentiation, maturation and functional activity. In the laboratory, it has been described as a critical immune modulator impacting cytokine (particularly IL-2 and IFN-γ) production, innate immune (NK cell) activity, and adaptive immunity.Five milligram vial size is ideal for acute experiments, dose-response studies, pilot protocols and the smaller quantities that many customers require either for testing or limited-scope projects.

Thymosin Alpha-1 vs Thymosin Beta-4

Both Thymosin Alpha-1 and Thymosin Beta-4 are thymic peptides but serve very different purposes in research:

• Thymosin Alpha-1 is mostly an immune modulator. It improves cytotoxic T cell maturation, cytokine balance, and adaptive immunity. It has been extensively studied in immune senescence, viral response, and models of immune restoration.

• In regenerative medicine and injury restitution models, Thymosin Beta-4 has primarily been studied for its abilities in actin-sequestering, wound healing, tissue remodelling and repairing activities, angiogenesis promotion & anti-inflammatory properties.

Whereas Thymosin Beta-4 acts via regulation of the cytoskeleton and tissue repair, Thymosin Alpha-1 is used to study restoration of the immune system, T-cell function, and adaptive immunity modulation in aging models or models with borderline immune function.

Research-Based Benefits of Thymosin Alpha-1( Only Applicable to Research Environment)

Thymosin Alpha-1 has been studied in laboratory and preclinical research for these major areas:

1. T-Cell Maturation and Function Agonist

Thymosin Alpha-1 promotes functional T-cell creation from immature T-cell progenitors. It strengthens T-cell receptor signaling and increases IL-2 receptor expression, promoting enhanced adaptive immune responses in experimental models.

2. Modulation of Cytokine Production

The studies show Thymosin Alpha-1 enhances production of IL-2, IFN-γ, and other Th1 cytokines and aids in balancing the Th1/Th2 responses. This makes it useful for research in immune regulation and inflammatory control.

3. Supports Natural Killer (NK) Cell Activity

Thymosin Alpha-1 has been shown to augment NK cell activity and cytotoxicity, and provide better innate immune surveillance in multiple models of immune challenge.

4. Promising Role in Immunosenescence and Ageing Studies

It is known that in aging animal models, Thymosin Alpha-1 has been shown to reverse age-related decline of T-cell function, thymic output, and overall immune competence.

5. Research into Antiviral and Immune Defense

Thymosin Alpha-1 is also commonly employed as an experimental treatment in research on immune responses to viral infections, for its effects as a vaccine adjuvant, and to support adaptive immunity in immunocompromised or stressed models.

6. Restoration of Immune Balance

It has shown potential in correcting immune dysregulation and supporting balanced immune responses in models of chronic inflammation or immune exhaustion.Note:All stated benefits are from preclinical, animal, or early-phase research studies. They are not therapeutic claims. Safety and effectiveness in humans have not yet been determined for the research peptide form.

Product Specifications – Thymosin Alpha-1

Peptide:Thymosin Alpha-1In the newest formulation:5 mg lyophilized powder in a vialPurity:≥98% (HPLC) (Research Grade)Pharmaceutical Form:Lyophilized (for better stability)Use:For laboratory research use onlyThymosin Alpha-1 5mg is a selective and highly useful research instrument for researchers interested in the areas of T-cell biology, cytokine signaling, immune modulation, immune senescence, antiviral responses or thymic function.